Urinary Elimination

Urine-Urine is composed of water, certain electrolytes, and various waste product that are filtered out of the blood system.

  • For the production of urine, the kidneys do not simply pick waste products out of the bloodstream and send them along for final disposal.
  • The kidneys' 2 million or more nephrons (about a million in each kidney) form urine by three precisely regulated processes
  1. Filtration
  2. Reabsorption 
  3. Secretion 

1. Filtration- 

  • Blood courses through the Glomeruli, much of its fluid, containing both useful chemicals and dissolved waste materials, soaks out of the blood through the membranes (Osmosis & Diffusion) 
  • It is then filtered and then flows into the Bowman's Capsule.
  • The product formed is collectively known as Glomerular Filtrate.
  • Glomerular Filtrate - Water, waste products, excess salts (Na+ & K+), glucose, and other chemicals that have been filtered out of the blood.

Glomerular Filtrate Rate-

  • Total rate of filtration of the glomerulus 
  • The normal rate is 125mL/min
  • 125mL/min 7500mL/hr  180L/day
  • But why don’t we excrete 180L of water per day?

2. Reabsorption-

  • Movement of substances out of the renal tubules back into the Blood capillaries  located around the tubules
  • Substances reabsorbed are water, glucose and other nutrients, and sodium (Na+) and other ions
  • Reabsorption begins in the proximal convoluted tubules and continues in the loop of Henle, distal convoluted tubules, and collecting tubules.
  • About 99% of the 180L of water that leave the blood each day by glomerular filtration returns to the blood from the proximal tubule through the process of Passive Reabsorpton.
  • Nutrient glucose is entirely reabsorbed back into the blood from the proximal tubules. In fact, it is actively transported out of the tubules and into the Peritubular Capllary Blood
  •  Sodium ions (Na+) and other ions are only partially reabsorbed from the renal tubules back into the blood.
  • Amount depends largely on how much salt we take in from the foods that we eat. ↑Na+ intake = ↓Na+ reabsorption in the blood

3. Secretion -

  • Substances move into the distal and collecting tubules from blood in the capillaries around these tubules
  •  Secretion is reabsorption in reverse
  • Reabsorption- substance from tubules - blood
  • Secretion - substance from blood - tubules
  • Substances are secreted through either an Active Transport Mecheanism or as a result of Diffusion across the membrane
  • Secretion plays a crucial role in maintaining the body's Acid-Base balance , another example of an important body function that the kidney participates in.

Composition of Urine

Chemical Concentration  in g/100ml urine
Water 95
Urea 2
Sodium  0.6
Chloride  0.6
Sulfate  0.18
Potassium  0.15
Phosphate  0.12
Creatinine 0.1
Ammonia  0.05
Uric acid 0.03
Calcium 0.015
Magnesium  0.01
Protein  -
Glucose  -

 

#