Urinary Elimination
Urine-Urine is composed of water, certain electrolytes, and various waste product that are filtered out of the blood system.
- For the production of urine, the kidneys do not simply pick waste products out of the bloodstream and send them along for final disposal.
- The kidneys' 2 million or more nephrons (about a million in each kidney) form urine by three precisely regulated processes
- Filtration
- Reabsorption
- Secretion
1. Filtration-
- Blood courses through the Glomeruli, much of its fluid, containing both useful chemicals and dissolved waste materials, soaks out of the blood through the membranes (Osmosis & Diffusion)
- It is then filtered and then flows into the Bowman's Capsule.
- The product formed is collectively known as Glomerular Filtrate.
- Glomerular Filtrate - Water, waste products, excess salts (Na+ & K+), glucose, and other chemicals that have been filtered out of the blood.
Glomerular Filtrate Rate-
- Total rate of filtration of the glomerulus
- The normal rate is 125mL/min
- 125mL/min 7500mL/hr 180L/day
- But why don’t we excrete 180L of water per day?
2. Reabsorption-
- Movement of substances out of the renal tubules back into the Blood capillaries located around the tubules
- Substances reabsorbed are water, glucose and other nutrients, and sodium (Na+) and other ions
- Reabsorption begins in the proximal convoluted tubules and continues in the loop of Henle, distal convoluted tubules, and collecting tubules.
- About 99% of the 180L of water that leave the blood each day by glomerular filtration returns to the blood from the proximal tubule through the process of Passive Reabsorpton.
- Nutrient glucose is entirely reabsorbed back into the blood from the proximal tubules. In fact, it is actively transported out of the tubules and into the Peritubular Capllary Blood
- Sodium ions (Na+) and other ions are only partially reabsorbed from the renal tubules back into the blood.
- Amount depends largely on how much salt we take in from the foods that we eat. ↑Na+ intake = ↓Na+ reabsorption in the blood
3. Secretion -
- Substances move into the distal and collecting tubules from blood in the capillaries around these tubules
- Secretion is reabsorption in reverse
- Reabsorption- substance from tubules - blood
- Secretion - substance from blood - tubules
- Substances are secreted through either an Active Transport Mecheanism or as a result of Diffusion across the membrane
- Secretion plays a crucial role in maintaining the body's Acid-Base balance , another example of an important body function that the kidney participates in.
Composition of Urine
Chemical | Concentration in g/100ml urine |
Water | 95 |
Urea | 2 |
Sodium | 0.6 |
Chloride | 0.6 |
Sulfate | 0.18 |
Potassium | 0.15 |
Phosphate | 0.12 |
Creatinine | 0.1 |
Ammonia | 0.05 |
Uric acid | 0.03 |
Calcium | 0.015 |
Magnesium | 0.01 |
Protein | - |
Glucose | - |